Implicating extracellular vesicles in <scp> <i>Plasmodium falciparum</i> </scp> artemisinin resistance development

Plasmodium falciparum malaria remains a disease of significant public health impact today. With the risk emerging artemisinin resistance stalling control efforts, need to deepen our understanding parasite's biology is dire. Extracellular vesicles (EVs) are vital P. and play role in pathogenesis malaria. Recent studies have also shown that EVs may development falciparum. Here, we highlight evidence on argue there sufficient ground propose for resistance. We suggest actively secreted functional organelles contribute cellular homeostasis falciparum-infected red blood cells under pressure. Further exploration this hypothesized EVs-based molecular mechanism will aid discovery novel antimalarial therapies.